
产品货号:
Z15873
中文名称:
DLL3抗体
英文名称:
Anti-DLL3 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DLL3 Antibody |
指标别名 | delta like 3 (Drosophila);Delta like protein 3;Delta3;DLL3;Drosophila Delta homolog 3;SCDO1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,ELISA |
基因名称 | DLL3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human DLL3 protein. |
计算分子量 | 65KD |
成分 | Liquid form in PBS containing 50% glycerol,and 0.02% sodium azide. |
纯化方式 | DLL3 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | DLL3(DELTA-LIKE 3) also known as DELTA,DROSOPHILA,HOMOLOG OF,is a protein which in humans is encoded by the DLL3 gene.This gene encodes a member of the delta protein ligand family.This family functions as Notch ligands that are characterized by a DSL domain,EGF repeats,and a transmembrane domain.Mutation in the mouse delta-like 3 gene(Dll3),which is homologous to the Notch-ligand delta in Drosophila,results in the mouse 'pudgy' phenotype.The human DLL3 gene was identified within a critical interval,mapped in 2 consanguineous Arab-Israeli and Pakistani SCDO1 pedigrees,of 7.8 cM at 19q13.1-q13.3 between D19S570 and D19S908(Bulman et al.,2000).Dunwoodie et al.(1997) presented results suggesting that mouse Dll3 may complement the function of other delta homologs during early pattern formation in the mouse embryo.In humans,the fact that mutations in genes required for oscillation,such as DLL3,result in abnormal segmentation of the vertebral column suggests that the segmentation clock also acts during human embryonic development.This residue is highly conserved in Delta proteins from Drosophila to humans,and the substitution of a charged polar for a nonpolar residue may disrupt the conformation of the DLL3 protein. |
Uniprot ID | Q9NYJ7 |
基因名全称 | Delta-like protein 3 |
蛋白名全称 | Delta-like protein 3 |
推荐稀释比 | WB 1:500~2000 ELISA 1:5000~20000 |
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